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disease 1,119 words KG: OVERVIEW
Contents

Diseases Overview

Disease Info
Associated GenesADAM17, ADH1B, AGING, AKT, AKT1, AKT2, ALPHA-SYNUCLEIN, ALS
KG Connections2123 knowledge graph edges
DatabasesOMIMOrphanetClinicalTrialsPubMed

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Knowledge Graph

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🌐 Cross-references

OMIMMeSHWikipedia

Related Hypotheses (70)

APOE Isoform Expression Across Glial Subtypes
Score: 0.74Smartphone-Detected Motor Variability Correction
Score: 0.74Senescent Cell Mitochondrial DNA Release
Score: 0.74APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.74PARP1 Inhibition Therapy
Score: 0.74Senescence-Associated Myelin Lipid Remodeling
Score: 0.73Senescence-Induced Lipid Peroxidation Spreading
Score: 0.73CYP46A1 Overexpression Gene Therapy
Score: 0.73Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.72Circadian Rhythm Entrainment of Reactive Astrocytes
Score: 0.72APOE Isoform Conversion Therapy
Score: 0.72Circadian-Synchronized LRP1 Pathway Activation
Score: 0.71Noradrenergic-Tau Propagation Blockade
Score: 0.71Membrane Cholesterol Gradient Modulators
Score: 0.71SASP-Mediated Complement Cascade Amplification
Score: 0.70Extracellular Matrix Stiffness Modulation
Score: 0.69Cross-Seeding Prevention Strategy
Score: 0.69CX43 hemichannel engineering enables size-selective mitochon
Score: 0.69TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.69
← Prevpg 2/4Next →

Related Analyses (24)

Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archivedSelective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archivedTDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archivedAstrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archivedBlood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (4)

adam17
gene · KG edge: implicated_inADORA2A Gene
gene · KG edge: regulatesAKT3 Gene
gene · KG edge: implicated_inAging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: activates

Knowledge Graph (12 edges)

IDH1 biomarker_for OVERVIEW
TERT biomarker_for OVERVIEW
JUN biomarker_for OVERVIEW
CIC biomarker_for OVERVIEW
FUBP1 biomarker_for OVERVIEW
H3F3A biomarker_for OVERVIEW
OVERVIEW biomarker_for BRAF
OVERVIEW biomarker_for ATRX
LETM1 regulates OVERVIEW
MCU regulates OVERVIEW

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