protein 936 words KG: CTSB
Contents

Cathepsin B Protein (CTSB)

🔬 Protein Info
Gene SymbolCTSB
Full NameCathepsin B
Chromosome8p23.1
Subcellular Localization** | Lysosomes, endosomes
Molecular Weight26 kDa
Amino Acids339 aa
Exons13
PathwaysAutophagy
UniProt IDP07846
NCBI Gene ID1508
Ensembl IDENSG00000164733
OMIM116810
GeneCardsCTSB
Human Protein AtlasCTSB
BrainExpressed in neurons, astrocytes, and microglia throughout the CNS
Associated DiseasesAging, Als, Alzheimer, Amyotrophic Lateral Sclerosis, APOPTOSIS
Known Drugs/Compoundsrapamycin, tannic acid
InteractionsACTB, Actin, AGING, AIF1, AKT, ALS
SciDEX HypothesesSelective cathepsin B inhibition prevents cathepsi
KG Connections815 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

UniProtWikipedia

Related Hypotheses (2)

Lysosomal Acidification Failure: Convergent GBA1/LAMP2A–medi
Score: 0.70
Selective cathepsin B inhibition prevents cathepsin leakage-
Score: 0.62

Knowledge Graph (12 edges)

CTSB activates C1QA
CTSB activates SPP1
CTSB activates GRN
STIP1 associated_with CTSB
LGALS3 associated_with CTSB
HSPA8 associated_with CTSB
MCOLN1 associated_with CTSB
SQSTM1 associated_with CTSB
SOD1 associated_with CTSB
BCL2 associated_with CTSB

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