Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NEUROPEPTIDE Y: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No summary available yet.
No AI portrait yet
| Name | NEUROPEPTIDE Y |
graph TD
NEUROPEPTIDE_Y[NEUROPEPTIDE Y]
NEUROPEPTIDE_Y -->|required_for| BDNF_NGFR_signaling[BDNF/NGFR signaling]
NEUROPEPTIDE_Y -->|released_by| neurons[neurons]
NEUROPEPTIDE_Y -->|active_in| hippocampus[hippocampus]
NEUROPEPTIDE_Y -->|released_by| interneurons[interneurons]
NEUROPEPTIDE_Y -->|active_in| prefrontal_cortex[prefrontal cortex]
NEUROPEPTIDE_Y -->|released_by| neural_stem_cells[neural stem cells]
NEUROPEPTIDE_Y -->|released_by| microglia[microglia]
ABCA7[ABCA7] -->|induces| NEUROPEPTIDE_Y
depression[depression] -->|disrupts| NEUROPEPTIDE_Y
BDNF[BDNF] -->|regulates| NEUROPEPTIDE_Y
Alzheimer_s_disease[Alzheimer's disease] -->|disrupts| NEUROPEPTIDE_Y
GABRA1[GABRA1] -->|implicated in| NEUROPEPTIDE_Y
SST[SST] -->|activates| NEUROPEPTIDE_Y
NMDA_receptor[NMDA receptor] -->|binds| NEUROPEPTIDE_Y| Target | Relation | Type | Str |
|---|---|---|---|
| neurons | released_by | cell_type | 0.80 |
| BDNF/NGFR signaling | required_for | pathway | 0.80 |
| hippocampus | active_in | brain_region | 0.70 |
| prefrontal cortex | active_in | brain_region | 0.60 |
| microglia | released_by | cell_type | 0.60 |
| interneurons | released_by | cell_type | 0.60 |
| neural stem cells | released_by | cell_type | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ABCA7 | induces | gene | 0.80 |
| depression | disrupts | disease | 0.70 |
| BDNF | regulates | gene | 0.70 |
| BDNF | activates | gene | 0.70 |
| Alzheimer's disease | disrupts | disease | 0.70 |
| schizophrenia | disrupts | disease | 0.60 |
| autism | disrupts | disease | 0.60 |
| PTSD | disrupts | disease | 0.60 |
| GABRA1 | implicated_in | gene | 0.60 |
| GABA | regulates | gene | 0.60 |
| GABA | biomarker_for | gene | 0.60 |
| neurodegeneration | disrupts | disease | 0.60 |
| SST | associated_with | gene | 0.60 |
| Parkinson's disease | disrupts | disease | 0.60 |
| SST | regulates | gene | 0.60 |
| BDNF | biomarker_for | gene | 0.60 |
| SST | biomarker_for | gene | 0.60 |
| SLC17A7 | associated_with | gene | 0.60 |
| PVALB | associated_with | gene | 0.60 |
| SNAP25 | associated_with | gene | 0.60 |
| HCN1 | activates | gene | 0.60 |
| HCN1 | regulates | gene | 0.60 |
| BDNF | implicated_in | gene | 0.60 |
| HCN1 | implicated_in | gene | 0.60 |
| SST | activates | gene | 0.60 |
| MTNR1A | associated_with | gene | 0.60 |
| NMDA receptor | binds | receptor | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning NEUROPEPTIDE Y in their description or question text
No additional research found