Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PODOCYTE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | PODOCYTE |
graph TD
PODOCYTE["PODOCYTE"]
PPAR["PPAR"] -->|"target for"| PODOCYTE
FERROPTOSIS["FERROPTOSIS"] -->|"activates"| PODOCYTE
GPX4_SLC7A11["GPX4/SLC7A11"] -->|"target for"| PODOCYTE
ACSL4["ACSL4"] -->|"target for"| PODOCYTE
PYROPTOSIS["PYROPTOSIS"] -->|"target for"| PODOCYTE
WT1["WT1"] -->|"expressed in"| PODOCYTE
PAX2["PAX2"] -->|"expressed in"| PODOCYTE
SALL1["SALL1"] -->|"expressed in"| PODOCYTE| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| HO-1 | associated_with | gene | 0.60 |
| FERROPTOSIS | activates | gene | 0.60 |
| PYROPTOSIS | therapeutic_target | gene | 0.60 |
| WT1 | expressed_in | gene | 0.60 |
| MIRNAS | biomarker_for | gene | 0.60 |
| MICRORNAS | biomarker_for | gene | 0.60 |
| FERROPTOSIS | contributes_to | gene | 0.60 |
| APOPTOSIS | contributes_to | gene | 0.60 |
| PYROPTOSIS | contributes_to | gene | 0.60 |
| AUTOPHAGY | contributes_to | gene | 0.60 |
| GSK3 | inhibits | gene | 0.60 |
| APOPTOSIS | inhibits | gene | 0.60 |
| IL-1 | inhibits | gene | 0.60 |
| IL-6 | inhibits | gene | 0.60 |
| NLRP3 | activates | gene | 0.60 |
| SMPD1 | activates | gene | 0.60 |
| TAK1 | inhibits | gene | 0.60 |
| OTUD5 | inhibits | gene | 0.60 |
| AKT | inhibits | gene | 0.60 |
| TLR4 | inhibits | gene | 0.60 |
| PI3K | inhibits | gene | 0.60 |
| MYD88 | inhibits | gene | 0.60 |
| NRF2 | associated_with | gene | 0.60 |
| PPAR | therapeutic_target | gene | 0.60 |
| GPX4/SLC7A11 | therapeutic_target | gene | 0.60 |
| ACSL4 | therapeutic_target | gene | 0.60 |
| PAX2 | expressed_in | gene | 0.60 |
| SALL1 | expressed_in | gene | 0.60 |
| Ferroptosis | contributes_to | disease | 0.55 |
| Ferroptosis | activates | disease | 0.55 |
| Fibrosis | activates | disease | 0.55 |
| Als | therapeutic_target | disease | 0.55 |
| Diabetes | therapeutic_target | disease | 0.55 |
| Als | expressed_in | disease | 0.55 |
| Diabetes | biomarker_for | disease | 0.55 |
| Als | biomarker_for | disease | 0.55 |
| Obesity | activates | disease | 0.55 |
| Als | inhibits | disease | 0.55 |
| Pyroptosis | contributes_to | disease | 0.55 |
| Pyroptosis | therapeutic_target | disease | 0.55 |
| Inflammasome | activates | pathway | 0.50 |
| Autophagy | contributes_to | pathway | 0.50 |
| Apoptosis | contributes_to | pathway | 0.50 |
| Pi3K/Akt | inhibits | pathway | 0.50 |
| Nf-Κb | inhibits | pathway | 0.50 |
| Oxidative Stress | activates | pathway | 0.50 |
| Apoptosis | inhibits | pathway | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning PODOCYTE in their description or question text
No additional research found