gene

sall1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about sall1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

26Connections

0Hypotheses

0Analyses

19Outgoing

7Incoming

0Experiments

0Debates

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🧬 Gene Info

Gene Symbol	SALL1
Aliases	Sal-like protein 1
Chromosome	16
Protein Type	Transcription Factor
Function	is a zinc-finger transcription factor that plays critical roles in embryonic development and cellular differentiation.
Primary Expression	all microglial subpopulations - Maintained in adult microglia throughout life - Not expressed in neurons, astrocytes, or oligodendrocytes - Specific t
Amino Acids	322 aa
Exons	Multiple exons encoding the full-length protein
GeneCards	SALL1
Human Protein Atlas	SALL1
Band	16q12.1
Genomic coordinates	Approximately 51,180,000-51,250,000 (GRCh38)
Gene length	Approximately 70 kb
Associated Diseases	Alzheimer's disease pathogenesis:
KG Connections	1 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

sall1

gene · 1646 words

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Pathway Diagram

graph TD
    SALL1["SALL1"]
    SALL1 -->|"expressed in"| Ms["Ms"]
    SALL1 -->|"expressed in"| Als["Als"]
    SALL1 -->|"expressed in"| ALS["ALS"]
    SALL1 -->|"expressed in"| AND["AND"]
    SALL1 -->|"expressed in"| Epithelial["Epithelial"]
    SALL1 -->|"expressed in"| Podocyte["Podocyte"]
    SALL1 -->|"expressed in"| Progenitor_Cell["Progenitor Cell"]

Outgoing (19)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:SALL1	data_in	dataset_row	0.00
TMEM119	activates	gene	0.65
Als	therapeutic_target	disease	0.65
ALS	expressed_in	disease	0.65
Ms	expressed_in	disease	0.65
Als	expressed_in	disease	0.65
PAX2	associated_with	gene	0.60
Epithelial	expressed_in	cell_type	0.60
Podocyte	expressed_in	cell_type	0.60
AND	expressed_in	gene	0.60
WT1	associated_with	gene	0.60
TREM2	activates	gene	0.55
Progenitor Cell	expressed_in	cell_type	0.55
microglia	expressed_in	cell_type	0.55
DAM microglia	expressed_in	cell_type	0.55
Stem Cell	expressed_in	cell_type	0.55
NF-kB signaling	participates_in	pathway	0.55
unfolded protein response	participates_in	pathway	0.55
PAX2	associated_with	gene	0.50

Incoming (7)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:SALL1	data_in	dataset_row	0.00
WT1	associated_with	gene	0.60
PAX2	associated_with	gene	0.60
HEXB	activates	gene	0.55
APOE	activates	gene	0.55
CX3CR1	activates	gene	0.55
P2RY12	activates	gene	0.55

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning sall1 in their description or question text

No additional research found