gene

PAX2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PAX2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

16Connections

0Hypotheses

0Analyses

12Outgoing

4Incoming

0Experiments

0Debates

Summary

Page for PAX2 Gene

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🧬 Gene Info

Gene Symbol	PAX2
Full Name	Paired Box 2
Chromosome	10q24.31
Protein Type	Transcription Factor
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	glioblastoma multiforme (GBM):
Amino Acids	417 aa
UniProt ID	Q02962
NCBI Gene ID	5076
Ensembl ID	ENSG00000175892
OMIM	167409
GeneCards	PAX2
Human Protein Atlas	PAX2
Associated Diseases	ALS
KG Connections	16 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: PAX2 — AlphaFold Q02962 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

PAX2 Gene

gene · 1176 words

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Pathway Diagram

graph TD
    PAX2["PAX2"]
    Ms{"Ms"}
    PAX2 -->|"expressed in"| Ms
    Als{"Als"}
    PAX2 -->|"expressed in"| Als
    PAX2 -->|"therapeutic target"| Als
    ALS{"ALS"}
    PAX2 -->|"expressed in"| ALS
    SALL1["SALL1"]
    PAX2 -->|"associated with"| SALL1
    Progenitor_Cell["Progenitor Cell"]
    PAX2 -->|"expressed in"| Progenitor_Cell
    Stem_Cell["Stem Cell"]
    PAX2 -->|"expressed in"| Stem_Cell
    neurodegeneration["neurodegeneration"]
    PAX2 -->|"implicated in"| neurodegeneration
    SALL1 -->|"associated with"| PAX2
    AND["AND"]
    AND -->|"expressed in"| PAX2
    style PAX2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (12)

Target	Relation	Type	Str
Als	therapeutic_target	disease	0.65
Ms	expressed_in	disease	0.65
Als	expressed_in	disease	0.65
ALS	expressed_in	disease	0.65
AND	expressed_in	gene	0.60
WT1	associated_with	gene	0.60
SALL1	associated_with	gene	0.60
Epithelial	expressed_in	cell_type	0.60
Podocyte	expressed_in	cell_type	0.60
ALS	associated_with	disease	0.60
Progenitor Cell	expressed_in	cell_type	0.55
Stem Cell	expressed_in	cell_type	0.55

Incoming (4)

Source	Relation	Type	Str
AND	expressed_in	gene	0.60
WT1	associated_with	gene	0.60
SALL1	associated_with	gene	0.60
sall1	associated_with	gene	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning PAX2 in their description or question text

No additional research found