concept

FOXD3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about FOXD3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

62Connections

0Hypotheses

0Analyses

42Outgoing

20Incoming

0Experiments

0Debates

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💡 Concept Info

Name	FOXD3
Key Genes/Proteins	AND, APOPTOSIS, BCL2L13, BRAIN INJURY, CANCER, DIABETES MELLITUS
Related Diseases	Cancer, Carcinoma, Diabetes
Related Pathways	Apoptosis, Epigenetic

Pathway Diagram

graph TD
    FOXD3["FOXD3"]
    FOXD3 -->|"activates"| MIR214["MIR214"]
    FOXD3 -->|"activates"| Inflammation["Inflammation"]
    FOXD3 -->|"activates"| Ischemia["Ischemia"]
    FOXD3 -->|"activates"| Ms["Ms"]
    FOXD3 -->|"expressed in"| Diabetes["Diabetes"]
    FOXD3 -->|"expressed in"| Cancer["Cancer"]
    FOXD3 -->|"expressed in"| Carcinoma["Carcinoma"]
    FOXD3 -->|"expressed in"| Stroke["Stroke"]
    BRAIN_INJURY["BRAIN INJURY"] -->|"activates"| FOXD3
    APOPTOSIS["APOPTOSIS"] -->|"inhibits"| FOXD3
    GAIN["GAIN"] -->|"regulates"| FOXD3
    KCNK2["KCNK2"] -->|"activates"| FOXD3

Outgoing (42)

Target	Relation	Type	Str
MIR214	activates	gene	0.72
Inflammation	regulates	disease	0.65
Spinal Cord Injury	activates	disease	0.65
Ischemia	regulates	disease	0.65
Stroke	expressed_in	disease	0.65
Carcinoma	expressed_in	disease	0.65
Ms	activates	disease	0.65
Inflammation	activates	disease	0.65
Ischemia	activates	disease	0.65
Diabetes	expressed_in	disease	0.65
Cancer	expressed_in	disease	0.65
SCII	activates	disease	0.64
INFLAMMATION	activates	gene	0.60
CANCER	expressed_in	gene	0.60
FOXM1	associated_with	gene	0.60
FOXP4	associated_with	gene	0.60
DIABETES MELLITUS	expressed_in	gene	0.60
FOXO4	associated_with	gene	0.60
FOXO1	associated_with	gene	0.60
FOXP2	associated_with	gene	0.60
Epigenetic	expressed_in	pathway	0.60
Hedgehog	expressed_in	pathway	0.60
FOXP3	associated_with	gene	0.60
FOXO3	associated_with	gene	0.60
GENES	expressed_in	gene	0.60
FOXK2	associated_with	gene	0.60
FOXA2	associated_with	gene	0.60
FOXG1	associated_with	gene	0.60
FOXO6	associated_with	gene	0.60
AND	associated_with	gene	0.60
GAIN	regulates	gene	0.60
Fus	activates	protein	0.60
KCNK2	activates	gene	0.60
Apoptosis	activates	pathway	0.60
SHH	expressed_in	gene	0.60
FOXN3	associated_with	gene	0.60
FOXP1	associated_with	gene	0.60
BCL2L13	expressed_in	gene	0.60
Apoptosis	inhibits	pathway	0.60
AND	activates	gene	0.60
APOPTOSIS	activates	phenotype	0.56
Spinal Cord	expressed_in	brain_region	0.55

Incoming (20)

Source	Relation	Type	Str
INFLAMMATION	activates	gene	0.60
BRAIN INJURY	activates	gene	0.60
APOPTOSIS	inhibits	gene	0.60
APOPTOSIS	activates	gene	0.60
GAIN	regulates	gene	0.60
KCNK2	activates	gene	0.60
FOXA2	associated_with	gene	0.60
FOXO6	associated_with	gene	0.60
FOXK2	associated_with	gene	0.60
FOXO3	associated_with	gene	0.60
FOXP3	associated_with	gene	0.60
FOXG1	associated_with	gene	0.60
ISCHEMIA	activates	disease	0.50
Spinal Cord	activates	cell_type	0.50
Microrna	activates	pathway	0.50
KCNK2	regulates	gene	0.50
KCNK2	expressed_in	gene	0.50
Spinal Cord	expressed_in	cell_type	0.50
apoptosis	activates	process	0.50
KCNK2	associated_with	gene	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning FOXD3 in their description or question text

No additional research found