concept

ADENOSINE RECEPTOR

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ADENOSINE RECEPTOR: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

44Connections

0Hypotheses

0Analyses

6Outgoing

38Incoming

0Experiments

0Debates

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💡 Concept Info

Name	ADENOSINE RECEPTOR

Pathway Diagram

graph TD
    ADENOSINE_RECEPTOR[ADENOSINE RECEPTOR]
    ADENOSINE_RECEPTOR -->|binds| adenosine[adenosine]
    ADENOSINE_RECEPTOR -->|expressed in| neurons[neurons]
    ADENOSINE_RECEPTOR -->|expressed in| cholinergic_neurons[cholinergic neurons]
    ADENOSINE_RECEPTOR -->|expressed in| blood_brain_barrier[blood-brain barrier]
    ADENOSINE_RECEPTOR -->|expressed in| microglia[microglia]
    ADENOSINE_RECEPTOR -->|expressed in| astrocytes[astrocytes]
    neurodegeneration[neurodegeneration] -->|involves| ADENOSINE_RECEPTOR
    DRP1[DRP1] -->|regulates| ADENOSINE_RECEPTOR
    AMBRA1[AMBRA1] -->|regulates| ADENOSINE_RECEPTOR
    BNIP3L[BNIP3L] -->|regulates| ADENOSINE_RECEPTOR
    ADORA2A[ADORA2A] -->|regulates| ADENOSINE_RECEPTOR
    BCL2[BCL2] -->|regulates| ADENOSINE_RECEPTOR
    DNM1L[DNM1L] -->|regulates| ADENOSINE_RECEPTOR
    BNIP3[BNIP3] -->|regulates| ADENOSINE_RECEPTOR

Outgoing (6)

Target	Relation	Type	Str
neurons	expressed_in	cell_type	0.90
adenosine	binds	neurotransmitter	0.90
blood-brain barrier	expressed_in	brain_region	0.60
microglia	expressed_in	cell_type	0.60
astrocytes	expressed_in	cell_type	0.60
cholinergic neurons	expressed_in	cell_type	0.60

Incoming (38)

Source	Relation	Type	Str
neurodegeneration	involves	disease	0.70
LRRK2	implicated_in	gene	0.60
prion disease	involves	disease	0.60
LRRK2	secreted_by	gene	0.60
GDNF	secreted_by	gene	0.60
GDNF	disrupts	gene	0.60
LRRK2	disrupts	gene	0.60
STING	activates	gene	0.60
MAPT	expressed_in	gene	0.60
STING	regulates	gene	0.60
DRP1	regulates	gene	0.60
AMBRA1	regulates	gene	0.60
BNIP3L	regulates	gene	0.60
DNM1L	regulates	gene	0.60
BNIP3	regulates	gene	0.60
DRP1	interacts_with	gene	0.60
AMBRA1	interacts_with	gene	0.60
BNIP3L	interacts_with	gene	0.60
ADORA2A	interacts_with	gene	0.60
BCL2	interacts_with	gene	0.60
DNM1L	interacts_with	gene	0.60
BNIP3	interacts_with	gene	0.60
TNF	causes	gene	0.60
anxiety	involves	disease	0.60
TNF	implicated_in	gene	0.60
depression	involves	disease	0.60
AMPK	phosphorylates	gene	0.60
NIX	regulates	gene	0.60
RNA	regulates	gene	0.60
Alzheimer's disease	involves	disease	0.60
NIX	interacts_with	gene	0.60
RNA	interacts_with	gene	0.60
CCL2	protects_against	gene	0.60
CCL2	treats	gene	0.60
GABA	expressed_in	gene	0.60
Parkinson's disease	involves	disease	0.60
ADORA2A	regulates	gene	0.60
BCL2	regulates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning ADENOSINE RECEPTOR in their description or question text

No additional research found