concept

AD RISK LOCI

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about AD RISK LOCI: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

34Connections

0Hypotheses

0Analyses

19Outgoing

15Incoming

0Experiments

0Debates

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💡 Concept Info

Name	AD RISK LOCI
Key Genes/Proteins	ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, AMYLOID-BETA, APOE, BIN1
Related Diseases	ALS, Alzheimer, Dementia
Related Pathways	Amyloid

Pathway Diagram

graph TD
    AD_RISK_LOCI["AD RISK LOCI"]
    AD_RISK_LOCI ---|"associated"| microglial_enhancers["microglial enhancers"]
    AD_RISK_LOCI ---|"associated"| Alzheimer["Alzheimer"]
    AD_RISK_LOCI ---|"associated"| Dementia["Dementia"]
    AD_RISK_LOCI ---|"associated"| Ms["Ms"]
    AD_RISK_LOCI ---|"associated"| ALS["ALS"]
    CR2["CR2"] ---|"associated"| AD_RISK_LOCI
    GENETIC_RISK_LOCI["GENETIC RISK LOCI"] ---|"associated"| AD_RISK_LOCI
    TREM2["TREM2"] ---|"associated"| AD_RISK_LOCI
    IL6["IL6"] ---|"associated"| AD_RISK_LOCI
    ZCWPW1["ZCWPW1"] ---|"associated"| AD_RISK_LOCI

Outgoing (19)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:AD RISK LOCI	data_in	dataset_row	0.00
microglial enhancers	associated_with	pathway	0.70
ALS	associated_with	disease	0.65
Ms	associated_with	disease	0.65
Alzheimer	associated_with	disease	0.65
Dementia	associated_with	disease	0.65
GBA	associated_with	gene	0.60
CR1	associated_with	gene	0.60
ALZHEIMER'S DISEASE	associated_with	gene	0.60
CTSH	associated_with	gene	0.60
PILRB	associated_with	gene	0.60
C16ORF95	associated_with	gene	0.60
BIN1	associated_with	gene	0.60
GMNC	associated_with	gene	0.60
AMYLOID-BETA	associated_with	gene	0.60
AMYLOID	associated_with	gene	0.60
TAU	associated_with	gene	0.60
Amyloid	associated_with	pathway	0.60
ALZHEIMER	associated_with	gene	0.60

Incoming (15)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:AD RISK LOCI	data_in	dataset_row	0.00
CR2	associated_with	gene	0.60
GENETIC RISK LOCI	associated_with	gene	0.60
TREM2	associated_with	gene	0.60
IL6	associated_with	gene	0.60
ZCWPW1	associated_with	gene	0.60
DEMENTIA	associated_with	gene	0.60
APOE	associated_with	gene	0.60
37774680	enriched in	paper	0.60
37774680	enriched for	paper	0.60
ALZHEIMER'S DISEASE	associated_with	gene	0.60
ALZHEIMER	associated_with	gene	0.60
AMYLOID-BETA	associated_with	gene	0.60
GMNC	associated_with	gene	0.60
C16ORF95	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning AD RISK LOCI in their description or question text

No additional research found