Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about C16ORF95: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | C16ORF95 |
| Key Genes/Proteins | AD RISK LOCI, ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, Amyloid-Beta, AMYLOID-BETA |
| Related Diseases | Als, ALS, Alzheimer |
| Related Pathways | Amyloid |
graph TD
C16ORF95["C16ORF95"]
C16ORF95 -->|"regulates"| phosphorylated_tau["phosphorylated tau"]
C16ORF95 ---|"associated"| Ptau["Ptau"]
C16ORF95 ---|"associated"| Lateral_Ventricular_Volume["Lateral Ventricular Volume"]
C16ORF95 ---|"associated"| Dementia["Dementia"]
C16ORF95 ---|"associated"| Alzheimer["Alzheimer"]
C16ORF95 ---|"associated"| ALS["ALS"]
DEMENTIA["DEMENTIA"] ---|"associated"| C16ORF95
APOE["APOE"] ---|"associated"| C16ORF95
AD_RISK_LOCI["AD RISK LOCI"] ---|"associated"| C16ORF95
ALZHEIMER["ALZHEIMER"] ---|"associated"| C16ORF95
CR1["CR1"] ---|"associated"| C16ORF95| Target | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:C16ORF95 | data_in | dataset_row | 0.00 |
| Ptau | associated_with | biomarker | 0.80 |
| Lateral Ventricular Volume | associated_with | phenotype | 0.75 |
| phosphorylated tau | regulates | protein | 0.70 |
| Als | associated_with | disease | 0.65 |
| Alzheimer | associated_with | disease | 0.65 |
| ALS | associated_with | disease | 0.65 |
| Dementia | associated_with | disease | 0.65 |
| AND | associated_with | gene | 0.60 |
| ALZHEIMER'S DISEASE | associated_with | gene | 0.60 |
| AMYLOID | associated_with | gene | 0.60 |
| TAU | associated_with | gene | 0.60 |
| BIN1 | associated_with | gene | 0.60 |
| Amyloid | associated_with | pathway | 0.60 |
| GMNC | associated_with | gene | 0.60 |
| AMYLOID-BETA | associated_with | gene | 0.60 |
| AD RISK LOCI | associated_with | gene | 0.60 |
| CR1 | associated_with | gene | 0.60 |
| APOE | associated_with | gene | 0.60 |
| DEMENTIA | associated_with | gene | 0.60 |
| Aβ | associated_with | protein | 0.60 |
| Amyloid-Beta | associated_with | protein | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:C16ORF95 | data_in | dataset_row | 0.00 |
| TAU | associated_with | gene | 0.60 |
| BIN1 | associated_with | gene | 0.60 |
| ALZHEIMER'S DISEASE | associated_with | gene | 0.60 |
| DEMENTIA | associated_with | gene | 0.60 |
| APOE | associated_with | gene | 0.60 |
| AD RISK LOCI | associated_with | gene | 0.60 |
| ALZHEIMER | associated_with | gene | 0.60 |
| CR1 | associated_with | gene | 0.60 |
| GMNC | associated_with | gene | 0.60 |
| AMYLOID-BETA | associated_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning C16ORF95 in their description or question text
No additional research found