| Gene Symbol | TUBG1 |
| Full Name | Tubulin Gamma 1 |
| Chromosome | 17q21.2 |
| Molecular Weight | 51 kDa |
| Amino Acids | 451 aa |
| Ensembl ID | ENSG00000131462 |
| GeneCards | TUBG1 |
| Human Protein Atlas | TUBG1 |
| Core structure | 13 gamma-tubulins arranged in a helical ring |
| Associated proteins | GCP2 (NEDD1), GCP3, GCP4, GCP5, GCP6 |
| Dimensions | ~25 nm diameter, ~8 nm thick |
| Template function | Provides 13-fold symmetry matching microtubule lattice |
| T7 loop | Mediates lateral interactions between gamma-tubulins |
| MIP domain | Interfaces with alpha/beta-tubulin dimers |
| Centrosomin-binding domain | Required for MTOC localization |
| Associated Diseases | neurodegeneration |
| Known Drugs/Compounds | rapamycin |
| Interactions | ACTB, ATG5, BECN1, CAT, CDKN1A, CTSD |
| KG Connections | 34 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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