Contents

TUBG1 — Tubulin Gamma 1

🧬 Gene Info

Gene Symbol	TUBG1
Full Name	Tubulin Gamma 1
Chromosome	17q21.2
Molecular Weight	51 kDa
Amino Acids	451 aa
Ensembl ID	ENSG00000131462
GeneCards	TUBG1
Human Protein Atlas	TUBG1
Core structure	13 gamma-tubulins arranged in a helical ring
Associated proteins	GCP2 (NEDD1), GCP3, GCP4, GCP5, GCP6
Dimensions	~25 nm diameter, ~8 nm thick
Template function	Provides 13-fold symmetry matching microtubule lattice
T7 loop	Mediates lateral interactions between gamma-tubulins
MIP domain	Interfaces with alpha/beta-tubulin dimers
Centrosomin-binding domain	Required for MTOC localization
Associated Diseases	neurodegeneration
Known Drugs/Compounds	rapamycin
Interactions	ACTB, ATG5, BECN1, CAT, CDKN1A, CTSD
KG Connections	34 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

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