| Gene Symbol | SNCAPROTEIN |
| Target Class | Structural Protein |
| Function | is a presynaptic protein of the central nervous system year: 1995 doi: 10. |
| Mechanism of Action | Immunotherapy targeting alpha-synuclein aggregates or small molecules preventing aggregation |
| Druggability | Medium (0.49) |
| Clinical Stage | Phase II |
| GeneCards | SNCAPROTEIN |
| Human Protein Atlas | SNCAPROTEIN |
| Associated Diseases | AD, Aging, ALI, Alpha-Synucleinopathies, Als |
| Known Drugs/Compounds | ACI-7104.056, AFFITOPE PD01A, ASO, Cinpanemab, D-520, levodopa |
| Interactions | ABCA7, ABCD3, ACETYL-COA, ACLY, aco2, ACO2 |
| SciDEX Target | View Target Profile (8 clinical trials) |
| SciDEX Hypotheses | Exosomal SNCA Propagation from Lysosome-Compromise SNCA Aggregation Hijacks the Endosomal Sorting Com m6A Hypermethylation of SNCA mRNA Stabilises Alpha (+5 more) |
| KG Connections | 2832 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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