protein 642 words KG: PP2APROTEIN
Contents

PP2A Protein

🔬 Protein Info
Gene SymbolPP2A
Full NameProtein Phosphatase 2 Scaffold Subunit A Alpha
AliasesPPP2R1A
Chromosome19q13.41
Protein TypeProtein
Molecular Weight65 kDa
PathwaysWnt, Notch pathway, mTOR, mtor, Wnt signaling
UniProt IDP30153
NCBI Gene ID5518
Ensembl IDENSG00000114825
OMIM605983
GeneCardsPP2A
Human Protein AtlasPP2A
Associated DiseasesAging, Als, Alzheimer, Alzheimer's disease, disease, neurodegeneration
Known Drugs/Compoundsdonepezil, Donepezil, DONEPEZIL, metformin, rapamycin, resveratrol
InteractionsAKT, AKT1, ALPHA-SYNUCLEIN, ALZHEIMER, ALZHEIMER'S DISEASE, AMBRA1
KG Connections343 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Related Hypotheses (9)

AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.82
Astroglial Gap Junction Coordination via Connexin-43 Phospho
Score: 0.72
Circadian Glymphatic Rescue Therapy (Melatonin-focused)
Score: 0.71
Sphingomyelin Synthase Activators for Raft Remodeling
Score: 0.69
FOXO3-Longevity Pathway Epigenetic Reprogramming
Score: 0.63
VCP-Mediated Autophagy Enhancement
Score: 0.59
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (11)

Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
Exosomal miR-155 in Neurodegeneration
biomarker · Pages share 5 hypotheses
Synaptic Biomarkers in Neurodegeneration
biomarker · Pages share 5 hypotheses
Liquid Biopsy in Neurodegeneration
biomarker · Pages share 5 hypotheses
Metabolomic Biomarkers in Neurodegeneration
biomarker · Pages share 5 hypotheses

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