| Gene Symbol | NOTCH3 |
| Full Name | Notch Receptor 3 |
| Aliases | Notch 3 |
| Chromosome | 19p13.12 |
| Protein Type | Receptor |
| Function | is a single-pass transmembrane receptor belonging to the Notch family of signaling proteins (NOTCH1-4 in mammals). |
| Primary Expression | Vascular smooth muscle cells, Pericytes, some neurons |
| Molecular Weight | 270 kDa |
| Amino Acids | 321 aa |
| Pathways | NOTCH, Notch, Notch Signaling, Notch signaling |
| UniProt ID | Q9UM47 |
| NCBI Gene ID | 4854 |
| Ensembl ID | ENSG00000074181 |
| OMIM | 600276 |
| GeneCards | NOTCH3 |
| Human Protein Atlas | NOTCH3 |
| Associated Diseases | Als, Alzheimer's disease |
| Interactions | AHR, ANGPT1, BACE1, CANCER, FLCN, GENES |
| KG Connections | 91 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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