| Gene Symbol | IRAK1 |
| Protein Family | IL-1 receptor-associated kinases |
| Protein Type | Serine/Threonine Kinase |
| Function | IRAK1 is a serine/threonine kinase recruited to activated TLR/IL-1R complexes via MyD88. |
| Subcellular Localization | the membrane, IRAK1 undergoes autophosphorylation and trans-phosphorylation by other IRAK family members, particularly I |
| Molecular Weight | 77 kDa |
| Amino Acids | 712 aa |
| Pathways | NF-κB, MAPK pathway, MAPK, NF-κB pathway |
| UniProt ID | [P51617](https://www.uniprot.org/uniprot/P51617) |
| GeneCards | IRAK1 |
| Human Protein Atlas | IRAK1 |
| Associated Diseases | neurodegeneration |
| Interactions | AKT, ASC, ASK1, ATF3, ATG5, CCR2 |
| KG Connections | 75 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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