| Gene Symbol | IL1R1 |
| Full Name | Interleukin 1 Receptor Type 1 |
| Chromosome | 2q12 |
| Protein Type | Receptor |
| Function | IL-1R1 mediates the potent pro-inflammatory effects of IL-1 cytokines in the central nervous system: |
| Subcellular Localization | </b></td><td>Cell membrane (type I transmembrane)</td></tr> |
| Molecular Weight | 80 kDa |
| Amino Acids | 319 aa |
| Pathways | NF-κB, MAPK |
| UniProt ID | [P01589](https://www.uniprot.org/uniprot/P01589) |
| Ensembl ID | ENSG00000115594 |
| GeneCards | IL1R1 |
| Human Protein Atlas | IL1R1 |
| Associated Diseases | Als, disease, Infection, Inflammation |
| Interactions | CCR2, Cytokine, IFN, Il-1, IL-1, Il-10 |
| KG Connections | 62 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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