| Gene Symbol | S100A9 |
| Full Name | S100 Calcium Binding Protein A9 |
| Chromosome | 1q21.3 |
| Protein Family | S100 calcium-binding protein family |
| Function | S100A9, particularly as part of calprotectin (S100A8/A9), has diverse functions |
| Molecular Weight | 13.2 kDa |
| Amino Acids | 113 aa |
| Exons | 3 |
| Pathways | NF-κB, MAPK signaling |
| GeneCards | S100A9 |
| Human Protein Atlas | S100A9 |
| EF-hand I (pseudo) | N-terminal non-functional calcium-binding site |
| EF-hand II (canonical) | C-terminal functional calcium-binding site |
| Hydrophobic patches | Mediate interaction with S100A8 and target proteins |
| C-terminal extension | Involved in dimerization and target recognition |
| Associated Diseases | Als, Ms, Neuroinflammation, Sepsis, stroke |
| Known Drugs/Compounds | GW201 |
| Interactions | ACE2, Actin, AGING, AIFM1, ALDH1A1, ALZHEIMER |
| KG Connections | 307 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!