Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MYORG: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | MYORG |
| Key Genes/Proteins | CMPK2, GENES, JAM2, JUN, MITOCHONDRIAL DYSFUNCTION, PARKINSON |
| Related Diseases | Aging, Als, ALS, Parkinson |
graph TD
MYORG["MYORG"]
MYORG -->|"expressed in"| White_Matter["White Matter"]
MYORG -->|"expressed in"| Thalamus["Thalamus"]
MYORG -->|"expressed in"| Cerebellum["Cerebellum"]
MYORG ---|"associated"| Primary_Familial_Brain_Calcifi["Primary Familial Brain Calcification"]
MYORG ---|"associated"| Parkinson["Parkinson"]
MYORG ---|"associated"| Aging["Aging"]
MYORG ---|"associated"| ALS["ALS"]
MYORG ---|"associated"| Als["Als"]
CMPK2["CMPK2"] ---|"associated"| MYORG
GENES["GENES"] ---|"associated"| MYORG
MITOCHONDRIAL_DYSFUNCTION["MITOCHONDRIAL DYSFUNCTION"] ---|"associated"| MYORG
JAM2["JAM2"] ---|"associated"| MYORG
PARKINSON["PARKINSON"] ---|"associated"| MYORG| Target | Relation | Type | Str |
|---|---|---|---|
| Primary Familial Brain Calcification | causes | disease | 0.95 |
| Primary Familial Brain Calcification | associated_with | disease | 0.95 |
| Als | associated_with | disease | 0.65 |
| Aging | associated_with | disease | 0.65 |
| ALS | associated_with | disease | 0.65 |
| Parkinson | associated_with | disease | 0.65 |
| PARKINSON'S DISEASE | associated_with | gene | 0.60 |
| XPR1 | associated_with | gene | 0.60 |
| JUN | associated_with | gene | 0.60 |
| Pdgf | associated_with | protein | 0.60 |
| Rb | associated_with | protein | 0.60 |
| MITOCHONDRIAL DYSFUNCTION | associated_with | gene | 0.60 |
| PDGFB | associated_with | gene | 0.60 |
| PDGFRB | associated_with | gene | 0.60 |
| GENES | associated_with | gene | 0.60 |
| JAM2 | associated_with | gene | 0.60 |
| PARKINSON | associated_with | gene | 0.60 |
| CMPK2 | associated_with | gene | 0.60 |
| PDGFB | interacts_with | gene | 0.60 |
| PDGFRB | interacts_with | gene | 0.60 |
| SLC20A2 | interacts_with | gene | 0.60 |
| XPR1 | interacts_with | gene | 0.60 |
| White Matter | expressed_in | brain_region | 0.55 |
| Thalamus | expressed_in | brain_region | 0.55 |
| Cerebellum | expressed_in | brain_region | 0.55 |
| Source | Relation | Type | Str |
|---|---|---|---|
| CMPK2 | associated_with | gene | 0.60 |
| GENES | associated_with | gene | 0.60 |
| MITOCHONDRIAL DYSFUNCTION | associated_with | gene | 0.60 |
| JAM2 | associated_with | gene | 0.60 |
| PARKINSON | associated_with | gene | 0.60 |
| SLC20A2 | associated_with | gene | 0.60 |
| PDGFB | associated_with | gene | 0.60 |
| JUN | associated_with | gene | 0.60 |
| PDGFRB | associated_with | gene | 0.60 |
| XPR1 | associated_with | gene | 0.60 |
| CMPK2 | interacts_with | gene | 0.60 |
| JAM2 | interacts_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning MYORG in their description or question text
No additional research found