gene 1,404 words KG: HSP27
Contents

HSPB1 — Heat Shock Protein Family B Member 1

🧬 Gene Info
Gene SymbolHSPB1
Full NameHeat Shock Protein Family B Member 1
AliasesHsp27
Chromosome7q11.23.
Molecular Weight27 kDa
Amino Acids205 aa
PathwaysMAPK Pathway, NF-κB, PI3K
GeneCardsHSPB1
Human Protein AtlasHSPB1
Basal state16-24 subunit oligomers
Stressed stateSmaller oligomers (8-12 mers) with increased chaperone activity
Phosphorylated stateDisassembly to dimers/tetramers
Associated DiseasesAging, Als, Alzheimer, Cardiovascular, disease, Ms
InteractionsActin, ALS, ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, AMYOTROPHIC LATERAL SCLEROSIS
SciDEX HypothesesHSPB1 Phosphorylation Mimetics to Promote Protecti
KG Connections321 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Knowledge Graph (12 edges)

P62 regulates HSP27
SQSTM1 regulates HSP27
HSP27 regulates SQSTM1
CTSH interacts_with HSP27
C1QB interacts_with HSP27
SOD1 activates HSP27
HSP27 regulates AKT
HSP70 therapeutic_target HSP27
CFTR regulates HSP27
HSP27 regulates UBIQUITIN

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