| Gene Symbol | XPC |
| Full Name | Xeroderma Pigmentosum Complementation Group C |
| Aliases | GG-NER |
| Chromosome | 3p25.1 |
| Function | encodes a protein critical for DNA nucleotide excision repair (NER). |
| Pathways | Apoptosis |
| UniProt ID | [Q01831](https://www.uniprot.org/uniprot/Q01831) |
| Ensembl ID | ENSG00000154767 |
| GeneCards | XPC |
| Human Protein Atlas | XPC |
| XPC | The DNA damage recognition subunit |
| RAD23B | Stabilizes XPC and links to the proteasome |
| CETN2 | Calcium-binding protein that aids in damage verification |
| DNA damage recognition domain | Binds to helix-distorting lesions |
| RAD23B-binding domain | Mediates complex formation |
| Associated Diseases | ALS, Cancer |
| Interactions | AKT, APOPTOSIS, DNA, LATS1, SIRT1, UVRAG |
| KG Connections | 20 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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