| Gene Symbol | WIPI1 |
| Aliases | WD Repeat Domain, Pyrin Interacting 1 |
| Chromosome | 1p34.2 |
| Protein Type | Gene |
| Function | WIPI1 localizes to the edges of the omegasome and is essential for the recruitment of downstream autophagy proteins (Proikas-Cezanne et al., 2004). |
| Molecular Weight | 49 kDa |
| Amino Acids | 449 aa |
| Exons | 10 |
| Pathways | Autophagy, Mitophagy, autophagy pathway, ubiquitin-proteasome |
| GeneCards | WIPI1 |
| Human Protein Atlas | WIPI1 |
| Phosphorylation | Multiple serine/threonine phosphorylation sites regulate WIPI1 activity and localization |
| Acetylation | Lysine acetylation modulates protein-protein interactions |
| Ubiquitination | May target WIPI1 for degradation under certain conditions |
| Associated Diseases | Als, Diabetes, Ms |
| Interactions | AMPK, AND, ATG, ATG16L1, AUTOPHAGY, BECN1 |
| KG Connections | 84 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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