gene 960 words KG: VPS37B
Contents

VPS37B Gene

🧬 Gene Info
Gene SymbolVPS37B
Full NameVacuolar Protein Sorting 37 Homolog B
Chromosome14q23.3
Functionis a core component of the ESCRT-I (Endosomal Sorting Complex Required for Transport-I) complex, critical for endosomal trafficking and multivesicular body (MVB) formation[@structure2009].
Molecular Weight21 kDa
Amino Acids184 aa
PathwaysAutophagy, Cell Cycle, Immune Response, Mtor
UniProt IDQ9H8Y8
NCBI Gene ID203197
Ensembl IDENSG00000139517
GeneCardsVPS37B
Human Protein AtlasVPS37B
Associated Diseasesneurodegeneration
KG Connections66 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (4)

Extracellular Vesicle Biogenesis Modulation
Score: 0.56
CYP46A1 Overexpression Gene Therapy
Score: 0.92
Autophagosome Maturation Checkpoint Control
Score: 0.71
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: regulates
Genes
index · KG edge: regulates
ADCY9 Gene
gene · KG edge: regulates
ADRA1D Gene
gene · KG edge: regulates
CALM2 Gene
gene · KG edge: regulates

Knowledge Graph (12 edges)

DNAJB6 associated_with VPS37B
VPS37B associated_with CHMP4B
PPP5C regulates VPS37B
JUN regulates VPS37B
ADRA1D regulates VPS37B
PDK4 regulates VPS37B
LITAF regulates VPS37B
IL6R regulates VPS37B
MERTK regulates VPS37B
DUSP1 regulates VPS37B

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