gene 1,549 words KG: MYH2
Contents

MYH2 Gene

🧬 Gene Info
Gene SymbolMYH2
AliasesMyosin Heavy Chain 2
FunctionMYH2 encodes the myosin heavy chain 2 (MyHC-IIa) protein, which is a member of the class II conventional myosin family.
Primary Expressionfast-twitch type 2a muscle fibers, which are characterized by:
Amino Acids240 aa
PathwaysAutophagy, Cell Cycle, Immune Response, Mtor
Ensembl IDENSG00000141349
GeneCardsMYH2
Human Protein AtlasMYH2
Rapid contractionType 2a fibers contract 2-3 times faster than slow type 1 fibers
High glycolytic capacityPrimarily use glycolysis for ATP production
Intermediate fatigue resistanceMore resistant to fatigue than type 2b fibers but less than type 1
Oxidative metabolismContain more mitochondria than type 2b fibers
Skeletal muscleHighest expression in fast-twitch skeletal muscle
Extraocular musclesHighly expressed in muscles controlling eye movements
Associated Diseasesneurodegeneration
KG Connections54 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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