gene 742 words KG: VKORC1L1
Contents

VKORC1L1 Gene - Vitamin K Epoxide Reductase Complex Subunit 1-Like 1

🧬 Gene Info
Gene SymbolVKORC1L1
Full NameVitamin K Epoxide Reductase Complex Subunit 1-Like 1
AliasesPage for VKORC1L1 Gene
Chromosome7q11.22
Protein TypeReductase
FunctionVitamin K metabolism
Primary ExpressionBrain, Liver, Lung, Heart
Amino Acids373 aa
PathwaysChemoresistance, Drug Resistance, Ferroptosis, Wnt
UniProt IDQ8N4U2
NCBI Gene ID89439
Ensembl IDENSG00000137868
GeneCardsVKORC1L1
Human Protein AtlasVKORC1L1
InteractionsCANCER, FERROPTOSIS, MDM2, P53, ROS, SLC7A11
KG Connections14 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Sphingolipid Metabolism Reprogramming
Score: 0.62
HSP90-Tau Disaggregation Complex Enhancement
Score: 0.57
Enteric Nervous System Prion-Like Propagation Blockade
Score: 0.48

Related Analyses (5)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (13)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Cytochrome Therapeutics
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40

See Also (7)

Neurodegeneration
disease · KG edge: implicated_in
Tumor Necrosis Factor (TNF)
entity · KG edge: activates
Ferroptosis Validation in Parkinson's Disease
experiment · KG edge: activates
MDM2 Gene
gene · KG edge: activates
SLC7A11 Gene - xCT Cystine/Glutamate Antiporter
gene · KG edge: activates

Knowledge Graph (12 edges)

SLC7A11 activates VKORC1L1
VKORC1L1 activates MDM2
ROS activates VKORC1L1
P53 activates VKORC1L1
FERROPTOSIS activates VKORC1L1
VKORC1L1 activates CANCER
VKORC1L1 activates Colorectal Cancer
VKORC1L1 activates Cancer
VKORC1L1 activates Tumor
VKORC1L1 activates Als

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