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gene 3,778 words KG: DDX3X
Contents

DDX3X Gene

🧬 Gene Info
Gene SymbolDDX3X
ChromosomeXp11.4
Functionis an ATP-dependent RNA helicase that belongs to the DEAD-box family of RNA helicases.
Molecular Weight73 kDa
Amino Acids662 aa
Exons17
PathwaysNF-κB, Wnt
GeneCardsDDX3X
Human Protein AtlasDDX3X
Associated DiseasesAls, Alzheimer, Autism, depression, neurodegeneration
InteractionsALS, AMYOTROPHIC LATERAL SCLEROSIS, C9ORF72, ERK1/2, G3BP1, IL-1
KG Connections91 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (15)

CYP46A1 Overexpression Gene Therapy
Score: 0.92APOE-Dependent Autophagy Restoration
Score: 0.85Epigenetic Memory Erasure via TET2 Activation
Score: 0.74Phase-Separated Organelle Targeting
Score: 0.73Stress Granule Phase Separation Modulators
Score: 0.72

Related Analyses (6)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · completedAstrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archivedNeuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archivedLipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completedCircuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (9)

Amyotrophic Lateral Sclerosis
redirect · KG edge: inhibitsApoptosis in Neurodegeneration
entity · KG edge: expressed_inc9orf72-als-ftd-phenotype-mechanism
general · KG edge: inhibitsC9orf72 — Chromosome 9 Open Reading Frame 72
gene · KG edge: inhibitscdkn2a
gene · KG edge: expressed_in

Knowledge Graph (12 edges)

P62 inhibits DDX3X
RAN regulates DDX3X
DDX3X inhibits C9ORF72
CDKN2A expressed_in DDX3X
TP53 expressed_in DDX3X
TET2 expressed_in DDX3X
MYD88 expressed_in DDX3X
KMT2D expressed_in DDX3X
STAT3 expressed_in DDX3X
DDX3X expressed_in RB1

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