gene 1,591 words KG: TRPM7
Contents

TRPM7 Gene

🧬 Gene Info
Gene SymbolTRPM7
Full NameTransient Receptor Potential Cation Channel Subfamily M Member 7
Chromosome15q21.3.
Protein TypeChannel
Functionis a unique bifunctional protein that combines an ion channel with a serine/threonine kinase domain.
Amino Acids2035 aa
Exons39
PathwaysBlood-Brain Barrier, pyroptosis
UniProt IDQ9BQZ6
NCBI Gene ID54822
Ensembl IDENSG00000156113
GeneCardsTRPM7
Human Protein AtlasTRPM7
Associated DiseasesCancer, status epilepticus
Known Drugs/CompoundsNS8593
InteractionsAND, App, AQP4, CHIP, EPILEPSY, IL-1
KG Connections149 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (11)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Transcriptional Autophagy-Lysosome Coupling
Score: 0.88
SASP-Driven Aquaporin-4 Dysregulation
Score: 0.78
Aquaporin-4 Polarization Rescue
Score: 0.73
Autophagosome Maturation Checkpoint Control
Score: 0.71

Related Analyses (4)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (8)

blarcamesine-axon
clinical_trial · KG edge: associated_with
Genes
index · KG edge: associated_with
AQP4 (Aquaporin-4 Gene)
gene · KG edge: activates
CACNA1B Gene
gene · KG edge: associated_with
CACNA1C Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

PIEZO1 associated_with TRPM7
KCNK2 associated_with TRPM7
SCN5A associated_with TRPM7
TRPM7 associated_with SCN1A
TRPM7 associated_with TRPV4
TRPM7 associated_with CACNA1B
TRPM7 associated_with SCNN1A
TRPM7 associated_with CFTR
TRPM7 associated_with PIEZO2
TRPM7 associated_with TRPA1

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