gene 1,170 words KG: SCN1A
Contents

SCN1A Gene

🧬 Gene Info
Gene SymbolSCN1A
Chromosome2q24.3
Primary ExpressionBrain (neurons, particularly GABAergic interneurons), heart
Molecular Weight226 kDa
Amino Acids2000 aa
UniProt IDP35499
NCBI Gene ID6335
Ensembl IDENSG00000144285
OMIM182389
GeneCardsSCN1A
Human Protein AtlasSCN1A
Associated DiseasesAls, Cancer, Epilepsy
InteractionsGENES, PVALB, SNAP25
KG Connections165 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (9)

Prefrontal sensory gating circuit restoration via PV interne
Score: 0.78
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Mechanosensitive Ion Channel Reprogramming
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Extracellular Matrix Stiffness Modulation
Score: 0.69
Reelin-Mediated Cytoskeletal Stabilization Protocol
Score: 0.69
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.67
Ephrin-B2/EphB4 Axis Manipulation
Score: 0.64
Synaptic Vesicle Tau Capture Inhibition
Score: 0.58

Related Analyses (6)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (7)

blarcamesine-axon
clinical_trial · KG edge: associated_with
Genes
index · KG edge: associated_with
CACNA1B Gene
gene · KG edge: associated_with
CACNA1C Gene
gene · KG edge: associated_with
CFTR Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

PIEZO1 associated_with SCN1A
KCNK2 associated_with SCN1A
SCN5A associated_with SCN1A
TRPM7 associated_with SCN1A
SCN1A associated_with TRPV4
SCN1A associated_with CACNA1B
SCN1A associated_with SCNN1A
SCN1A associated_with CFTR
SCN1A associated_with PIEZO2
SCN1A associated_with TRPA1

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