gene 1,846 words KG: TNFRSF13C
Contents

BAFFR Gene (TNFRSF13C)

🧬 Gene Info
Gene SymbolBAFFR
Full NameB Cell Activating Factor Receptor
Chromosome22q12.1
Protein TypeType I transmembrane receptor
FunctionMice lacking BAFFR (Tnfrsf13c knockout) or BAFF have severely reduced mature B cell numbers - B cell maturation: BAFFR is essential for the transition of transitional B cells to mature B cells in the
Molecular Weight~19.2 kDa
Amino Acids184 aa
Exons5
UniProt IDQ9Y239
GeneCardsBAFFR
Human Protein AtlasBAFFR
Associated DiseasesAtaxia, disease, Neurodegeneration, Spinocerebellar Ataxia
InteractionsADRA2B, AND, ASTROCYTE, CHRM4, CHRNE, CRH
KG Connections66 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (4)

Oligodendrocyte White Matter Vulnerability
Score: 0.65
CYP46A1 Overexpression Gene Therapy
Score: 0.92
APOE-Dependent Autophagy Restoration
Score: 0.85
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

GABA (Gamma-Aminobutyric Acid) - Neurodegenerative Dise
biomarker · KG edge: activates
Neurodegeneration
disease · KG edge: associated_with
astrocyte-neuron-metabolic-coupling-parkinsons
general · KG edge: activates
Oligodendrocyte-Myelin Dysfunction Validation in Parkin
experiment · KG edge: associated_with
Genes
index · KG edge: activates

Knowledge Graph (12 edges)

CHRM4 activates TNFRSF13C
MYO7A activates TNFRSF13C
GRM2 activates TNFRSF13C
WNT1 activates TNFRSF13C
CRH activates TNFRSF13C
ADRA2B activates TNFRSF13C
IL13 activates TNFRSF13C
CHRNE activates TNFRSF13C
WNT11 activates TNFRSF13C
GRIN3B activates TNFRSF13C

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