gene 2,073 words KG: SND1
Contents

SND1 — Stonin 1

🧬 Gene Info
Gene SymbolSND1
Full NameStonin 1
Chromosome1p36.22
Protein TypeAdaptor Protein
Functionencodes a specialized adaptor protein that plays a critical role in synaptic vesicle endocytosis.
Primary Expressionneurons throughout the central nervous system, with particularly high levels in the hippocampus, cerebral cortex, and cerebellum
Molecular Weight85 kDa
Amino Acids758 aa
Exons27
UniProt ID[Q9Y285](https://www.uniprot.org/uniprotkb/Q9Y285)
Ensembl IDENSG00000163511
OMIM607417
GeneCardsSND1
Human Protein AtlasSND1
Associated Diseasesneurodegeneration
InteractionsCANCER, FMR1, G3BP1, NONO, NPM1, SQSTM1
KG Connections28 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (4)

Phase-Separated Organelle Targeting
Score: 0.73
Stress Granule Phase Separation Modulators
Score: 0.72
RNA Granule Nucleation Site Modulation
Score: 0.66
Nucleolar Stress Response Normalization
Score: 0.65

Related Analyses (2)

RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (13)

Neurodegeneration
disease · KG edge: implicated_in
Diseases Overview
disease · KG edge: therapeutic_target
Apoptosis in Neurodegeneration
entity · KG edge: therapeutic_target
astrocyte-neuron-metabolic-coupling-parkinsons
general · KG edge: therapeutic_target
Genes
index · KG edge: therapeutic_target

Knowledge Graph (12 edges)

NPM1 interacts_with SND1
G3BP1 interacts_with SND1
NONO interacts_with SND1
SQSTM1 interacts_with SND1
FMR1 interacts_with SND1
PI3K therapeutic_target SND1
AKT therapeutic_target SND1
OVERVIEW therapeutic_target SND1
CANCER interacts_with SND1
SND1 interacts_with Ms

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.