| Gene Symbol | NONO |
| Full Name | Non-POU Domain Containing Octamer Binding |
| Chromosome | Xq13.1 |
| Protein Type | RNA-binding protein, DBHS family |
| Function | encodes a nuclear RNA-binding protein that belongs to the DBHS (Drosophila Behavior and Human Splicing) protein family. |
| Molecular Weight | 54 kDa |
| UniProt ID | [Q13435](https://www.uniprot.org/uniprot/Q13435) |
| Ensembl ID | ENSG00000147140 |
| OMIM | 300084 |
| GeneCards | NONO |
| Human Protein Atlas | NONO |
| N-terminal region | Involved in protein-protein interactions |
| DBHS domain | Conserved region comprising two RNA recognition motifs (RRMs) and an HTH (helix-turn-helix) domain |
| C-terminal region | Mediates multimerization and nuclear localization |
| SFPQ-NONO heterodimer | Primary functional complex for RNA processing |
| Associated Diseases | neurodegeneration |
| Interactions | CANCER, FMR1, FUS, G3BP1, MUC1, MYC |
| KG Connections | 13 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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