gene 1,224 words KG: RBFOX1
Contents

RNA Binding Fox-1 Homolog 1 (RBFOX1)

🧬 Gene Info
Gene SymbolRBFOX1
Full NameRNA Binding Fox-1 Homolog 1 (RBFOX1)
AliasesA2BP1
Chromosome16p13.3 [@zha2023]
Protein TypeGene
FunctionNeuronal Splicing Programs: Controls inclusion/exclusion of alternative exons in hundreds of neuronal transcripts.
Subcellular Localizationpattern, localizing to the nucleus where it participates in splicing compartments, to the cytoplasm where it regulates R
Molecular Weight47.6 kDa
Amino Acids90 aa
UniProt IDQ9NWB1
NCBI Gene ID23027
Ensembl IDENSG00000078328
GeneCardsRBFOX1
Human Protein AtlasRBFOX1
Associated DiseasesAls, Alzheimer, dementia, Ms, neurodegeneration
InteractionsANO3
KG Connections12 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (6)

Cross-Seeding Prevention Strategy
Score: 0.69
Biorhythmic Interference via Controlled Sleep Oscillations
Score: 0.66
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Trans-Synaptic Adhesion Molecule Modulation
Score: 0.54
Cryptic Exon Silencing Restoration
Score: 0.53

Related Analyses (9)

How do dilncRNAs specifically drive molecular crowding and p
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD AD
neurodegeneration · archived
What determines the specificity of DDR protein recruitment t
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived

Related Experiments (30)

FLS Stimulation and Transcriptomic Analysis
exploratory · proposed · Score: 0.95
Single-cell RNA-seq analysis of mouse testes with gonadal de
exploratory · proposed · Score: 0.95
Myricanol treatment in HFD-induced hyperlipidemic C57BL/6J m
validation · proposed · Score: 0.95
Sevoflurane-induced neurotoxicity (SIN) rat model
validation · proposed · Score: 0.95
LINC00599 expression analysis in hypoxic PH models
exploratory · proposed · Score: 0.90

See Also (5)

Neurodegeneration
disease · KG edge: implicated_in
Neurons
entity · KG edge: expressed_in
ANO3 Gene
gene · KG edge: interacts_with
u2af2
gene · KG edge: associated_with
Packard Center for ALS Research
institution · KG edge: associated_with

Knowledge Graph (12 edges)

RBFOX1 associated_with U2AF2
ANO3 interacts_with RBFOX1
FOXA2 co_expressed_with RBFOX1
PSMA3 co_expressed_with RBFOX1
RBFOX1 associated_with neurodegeneration
RBFOX1 associated_with Als
RBFOX1 associated_with Ms
RBFOX1 expressed_in neurons
RBFOX1 interacts_with amyloid aggregation
RBFOX1 associated_with ALS

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