| Gene Symbol | PNPLA6 |
| Full Name | Patatin-like Phospholipase Domain Containing 6 (Neuropathy Target Esterase, NTE) |
| Chromosome | 19p13.2 |
| Protein Type | Enzyme |
| Function | is a critical enzyme for neuronal health and axonal maintenance. |
| Primary Expression | Neurons, axons, peripheral nerve, Sertoli cells |
| Subcellular Localization | the endoplasmic reticulum and plasma membrane of neurons, with its catalytic domain facing the cytoplasm |
| Molecular Weight | 180 kDa |
| Amino Acids | 1640 aa |
| UniProt ID | Q8IY84 |
| NCBI Gene ID | 10908 |
| Ensembl ID | ENSG00000118640 |
| OMIM | 603649 |
| GeneCards | PNPLA6 |
| Human Protein Atlas | PNPLA6 |
| Associated Diseases | Ataxia, Cancer, Ms |
| KG Connections | 52 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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