gene 747 words KG: SIL1
Contents

SIL1 Gene

🧬 Gene Info
Gene SymbolSIL1
Full NameSIL1 Nucleotide Exchange Factor
Chromosome5q31.2
Protein TypeChaperone
FunctionBy stimulating ATP hydrolysis and substrate release from BiP, SIL1 facilitates the protein folding cycle in the ER lumen.
Molecular Weight52 kDa
UniProt IDQ9H3K5
NCBI Gene ID22954
Ensembl IDENSG00000135902
OMIM608005
GeneCardsSIL1
Human Protein AtlasSIL1
Associated DiseasesAtaxia, Ms
KG Connections19 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (3)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
R-Loop Resolution Enhancement Therapy
Score: 0.68

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (12)

Neurodegeneration
disease · KG edge: implicated_in
ATM Gene
gene · KG edge: associated_with
CLPP (Caseinolytic Mitochondrial Matrix Peptidase Prote
gene · KG edge: associated_with
FMR1 — Fragile X Messenger Ribonucleoprotein 1
gene · KG edge: associated_with
HARS1 — Histidyl-tRNA Synthetase 1
gene · KG edge: associated_with

Knowledge Graph (12 edges)

WFS1 associated_with SIL1
HARS associated_with SIL1
ATM associated_with SIL1
CLPP associated_with SIL1
SETX associated_with SIL1
LARS2 associated_with SIL1
POLG associated_with SIL1
SIL1 associated_with STUB1
SIL1 associated_with FMR1
SIL1 associated_with TWNK

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