gene 1,021 words KG: P2RX5
Contents

P2RX5 Gene

🧬 Gene Info
Gene SymbolP2RX5
Chromosome17p13.1
Protein TypeChannel
Functionencodes a member of the P2X family of ATP-gated ion channels.
Primary Expressionvarious tissues including lymphoid organs, bladder, and parts of the nervous system, with roles in immune function, sensory signaling, and more recent
Amino Acids422 aa
NCBI Gene ID5026
GeneCardsP2RX5
Human Protein AtlasP2RX5
Associated DiseasesAls, Inflammation
Interactionsadora2b, ADORA2B, F3, GENES, P2RX1, P2RX4
KG Connections44 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (6)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
Purinergic Signaling Polarization Control
Score: 0.71
Purinergic P2Y12 Inverse Agonist Therapy
Score: 0.70
Microglial Purinergic Reprogramming
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Gap Junction Hemichannel Modulation for Controlled Mitochond
Score: 0.36

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Synaptic pruning by microglia in early AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Leukocyte gene expression analysis in COVID-19 patients
exploratory · proposed · Score: 0.90

See Also (12)

ATP P2X3 Receptor Neurons
cell · KG edge: associated_with
nad-augmentation-therapy-early-ad
general · KG edge: associated_with
Genes
index · KG edge: activates
ADORA2B Gene
gene · KG edge: activates
CD38 Molecule (CD38)
gene · KG edge: associated_with

Knowledge Graph (12 edges)

ADORA2B activates P2RX5
P2RY12 activates P2RX5
P2RX1 activates P2RX5
P2RX4 activates P2RX5
P2RX7 activates P2RX5
CD38 associated_with P2RX5
P2RY1 activates P2RX5
P2RX5 activates PANX1
PANX1 activates P2RX5
P2RX5 activates P2RY12

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