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gene 639 words KG: NRXN3
Contents

NRXN3 Gene

🧬 Gene Info
Gene SymbolNRXN3
Chromosome14q31.1.
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressioncerebral cortex (layer 2/3 pyramidal neurons), hippocampus (CA1-CA3, dentate gyrus), striatum (
Molecular Weight180 kDa
Exons24
PathwaysOxidative Stress, Sod1
GeneCardsNRXN3
Human Protein AtlasNRXN3
Associated DiseasesALS, Alzheimer
InteractionsAND, Bdnf, BDNF, CAT, COX4I1, CYCS
KG Connections77 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (6)

Trans-Synaptic Adhesion Molecule Modulation
Score: 0.54CYP46A1 Overexpression Gene Therapy
Score: 0.92Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.81Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.74

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archivedLipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completedTau propagation mechanisms and therapeutic interception poin
neurodegeneration · archivedCircuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Neuroinflammation PET Imaging in CBS/PSP
diagnostic · KG edge: protects_againstNeurodegeneration
disease · KG edge: protects_againstGenes
index · KG edge: inhibitsBDNF Gene
gene · KG edge: inhibitsCAT — Catalase
gene · KG edge: inhibits

Knowledge Graph (12 edges)

NRXN3 inhibits PDHA1
NRXN3 inhibits BDNF
NRXN3 inhibits PRKAA1
NRXN3 protects_against SOD2
NRXN3 inhibits SOD1
NRXN3 inhibits NLGN2
NRXN3 protects_against PSD95
NRXN3 inhibits CYCS
NRXN3 inhibits CAT
NRXN3 inhibits SLC2A2

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