| Gene Symbol | SLC2A2 |
| Aliases | GLUT2 |
| Protein Type | Gene |
| Function | Unlike high-affinity glucose transporters such as GLUT1 (SLC2A1) or GLUT3 (SLC2A3), GLUT2 has a relatively low affinity for glucose (Km ~15-20 mM), which makes it well-suited for tissues where glucose |
| Primary Expression | tissues critical for metabolic homeostasis, including the liver, pancreas, intestine, kidney, and specific brain regions |
| GeneCards | SLC2A2 |
| Human Protein Atlas | SLC2A2 |
| Pancreas | Highly expressed in pancreatic beta cells where it mediates glucose-stimulated insulin secretion |
| Liver | Expressed in hepatocytes where it participates in glucose uptake and hepatic glucose metabolism |
| Associated Diseases | neurodegeneration |
| Interactions | ABCC8, AND, Bdnf, BDNF, CAT, COX4I1 |
| KG Connections | 57 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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