| Gene Symbol | NPY1R |
| Aliases | Neuropeptide Y Receptor Y1 |
| Function | is a Class A rhodopsin-family GPCR that plays critical roles in regulating feeding behavior, energy homeostasis, emotional responses, synaptic plasticity, and seizure threshold [1](https://pubmed. |
| Primary Expression | brain regions involved in energy homeostasis, emotional processing, and memory: |
| Amino Acids | 384 aa |
| Pathways | MAPK pathway |
| Ensembl ID | ENSG00000118322 |
| GeneCards | NPY1R |
| Human Protein Atlas | NPY1R |
| BIBP3226 | First selective non-peptide antagonist |
| NPY 3-36 | Y1 antagonist (prefers Y2/Y5) |
| Leu^31-Pro^34]-NPY | Y1 agonist |
| Associated Diseases | Als, Asthma |
| Interactions | Albumin, INFLAMMATION, NPY |
| KG Connections | 101 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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