gene 1,544 words KG: NFATC2
Contents

NFATc2 — Nuclear Factor of Activated T Cells 2

🧬 Gene Info
Gene SymbolNFATc2 / NFATC2
AliasesNFATC2
Chromosome20q13.12
Protein TypeTranscription Factor
Functionis a member of the NFAT (Nuclear Factor of Activated T cells) transcription factor family involved in calcium-dependent gene regulation.
Subcellular Localizationand protein interactions
Amino Acids925 aa
Pathwayscascade: [@crabtree2001]
UniProt IDQ13469
NCBI Gene ID4778
Associated Diseasesneurodegeneration
InteractionsAKT, AURKA, AUTOPHAGY, CANCER, CTSB, LC3
KG Connections33 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

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Related Hypotheses (3)

Gamma entrainment therapy to restore hippocampal-cortical sy
Score: 0.90
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75

Related Analyses (1)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (5)

Blood Biomarker vs Tau PET for Treatment Monitoring
clinical · proposed · Score: 0.40
cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40
Exercise-BDNF-Mitophagy Biomarker Study in PD
clinical · proposed · Score: 0.40
Levodopa-Induced Dyskinesias Mechanism — Experiment Design
validation · proposed · Score: 0.40
Spinocerebellar Ataxia (SCA) Disease-Modifying Therapy Devel
validation · proposed · Score: 0.40

See Also (11)

Microglia
cell · KG edge: activates
Parkinson Basal Ganglia Circuit
circuit · KG edge: regulates
Microglia in Neurodegeneration
entity · KG edge: activates
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: activates
Genes
index · KG edge: regulates

Knowledge Graph (12 edges)

PI3K activates NFATC2
TPX2 activates NFATC2
LC3 activates NFATC2
AURKA activates NFATC2
AKT activates NFATC2
VEGFA activates NFATC2
NFATC2 activates CTSB
AUTOPHAGY activates NFATC2
CANCER activates NFATC2
NFATC2 activates Cancer

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