| Gene Symbol | NAIP |
| Full Name | NLR Apoptosis Inhibitor Protein |
| Chromosome | 5q13.2 |
| Protein Family | NLR family (BIRC family) |
| Protein Type | Receptor |
| Function | is a member of the NLR (NOD-like receptor) family of proteins that functions as both a pattern recognition receptor in innate immunity and an inhibitor of apoptosis. |
| Primary Expression | neurons and glial cells, where it participates in neuroinflammatory processes relevant to neurodegenerative diseases including Alzheimer's disease (AD |
| Amino Acids | 658 aa |
| Pathways | Inflammasome, Toll-Like Receptor, apoptosis pathway, pyroptosis |
| UniProt ID | P25116 |
| NCBI Gene ID | 4669 |
| Ensembl ID | ENSG00000140030 |
| OMIM | 147450 |
| GeneCards | NAIP |
| Human Protein Atlas | NAIP |
| Associated Diseases | Als, Cancer, Cardiovascular, Colorectal Cancer, Dementia |
| Interactions | AIM2, APOPTOSIS, Caspase, CYTOKINES, INFLAMMATION, NLR |
| KG Connections | 109 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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