gene 1,026 words KG: IGF2
Contents

IGF2 (Insulin-Like Growth Factor 2)

🧬 Gene Info
Gene SymbolIGF2
AliasesInsulin-Like Growth Factor 2
FunctionIGF2 serves multiple physiological functions
Molecular Weight7.5 kDa
Amino Acids24 aa
PathwaysBlood-Brain Barrier
UniProt ID[P01344](https://www.uniprot.org/uniprot/P01344)
NCBI Gene ID3481
GeneCardsIGF2
Human Protein AtlasIGF2
Associated DiseasesAls, Alzheimer, Alzheimer's disease
InteractionsAGING, AKT, AKT1, ALS, ALZHEIMER, amyotrophic lateral sclerosis
KG Connections185 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (10)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.38
APOE-Dependent Autophagy Restoration
Score: 0.88
Stress Granule Phase Separation Modulators
Score: 0.72
Lysosomal Enzyme Trafficking Correction
Score: 0.71
SASP-Mediated Complement Cascade Amplification
Score: 0.70
Axonal RNA Transport Reconstitution
Score: 0.70
Mitochondrial RNA Granule Rescue Pathway
Score: 0.66
Enteric Nervous System Prion-Like Propagation Blockade
Score: 0.48
Metabolic Switch Targeting for A1→A2 Repolarization
Score: 0.73
Metabolic Circuit Breaker via Lipid Droplet Modulation
Score: 0.71

Related Analyses (8)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (9)

Amyotrophic Lateral Sclerosis
redirect · KG edge: associated_with
Apoptosis in Neurodegeneration
entity · KG edge: inhibits
AKT1 Gene
gene · KG edge: inhibits
BAX Gene
gene · KG edge: activates
BCL2 Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

JUN expressed_in IGF2
IGF2 expressed_in IGF2R
IGF2 expressed_in JUN
IGF2 regulates RB1
IGF2 regulates RB1CC1
IGF2 activates learning and memory
IGF2 interacts_with IGF2R
RB1 regulates IGF2
IGF2R expressed_in IGF2
IGF2 associated_with Huntington's Disease

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.