gene 1,853 words KG: GOT1
Contents

GOT1 Gene

🧬 Gene Info
Gene SymbolGOT1
Full NameGlutamic-Oxaloacetic Transaminase 1
Chromosome10q24.3
Protein TypeEnzyme
FunctionAmino acid metabolism — Interconversion of aspartate and glutamate
Molecular Weight45 kDa
Amino Acids413 aa
Exons11
PathwaysFerroptosis, Proteasome, Ubiquitin-Proteasome
UniProt IDP17174
NCBI Gene ID2805
Ensembl IDENSG00000163283
OMIM138150
GeneCardsGOT1
Human Protein AtlasGOT1
Associated DiseasesCarcinoma, Hepatocellular Carcinoma
InteractionsACSL4, ACTB, ATG, BECLIN1, BECN1, COL1A1
KG Connections73 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (4)

ACSL4-Driven Ferroptotic Priming in Disease-Associated Micro
Score: 0.87
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.65
Blocking AGE-RAGE Signaling in Enteric Glia to Prevent Neuro
Score: 0.61

Related Analyses (3)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Cell type vulnerability in Alzheimers Disease (SEA-AD transc
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (12)

Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: associated_with
Ferroptosis Validation in Parkinson's Disease
experiment · KG edge: activates
ACSL4 Gene - Acyl-CoA Synthetase Long Chain Family Memb
gene · KG edge: activates
ACTB Gene
gene · KG edge: associated_with
BECN1 Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

GOT1 associated_with SQSTM1
GOT1 associated_with GPT
GOT1 associated_with ELAVL1
GOT1 associated_with GPX4
GOT1 activates BECLIN1
GOT1 associated_with P62
GOT1 associated_with FTH1
GOT1 associated_with MAP1LC3B
GOT1 associated_with TGFB1
GOT1 associated_with BECN1

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