gene 1,902 words KG: CXCR4
Contents

CXCR4 Gene

🧬 Gene Info
Gene SymbolCXCR4
AliasesC-X-C chemokine receptor type 4
Chromosome2q22.1
Protein TypeReceptor
FunctionCXCR4 has diverse physiological roles
Molecular Weight39.8 kDa
Amino Acids352 aa
PathwaysNF-κB, PI3K, MAPK pathway, MAPK
GeneCardsCXCR4
Human Protein AtlasCXCR4
Associated DiseasesAls, Alzheimer, Autoimmune, Breast Cancer, Cancer, dementia
InteractionsAGING, ALZHEIMER'S DISEASE, APOE, APOPTOSIS, APP, AUTOPHAGY
KG Connections301 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (22)

Fractalkine Axis Amplification via CX3CR1 Positive Allosteri
Score: 0.56
Synthetic Biology Approach: Designer Mitochondrial Export Sy
Score: 0.51
← Prevpg 2/2

Related Analyses (9)

Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived

See Also (11)

blarcamesine-axon
clinical_trial · KG edge: activates
Apoptosis in Neurodegeneration
entity · KG edge: activates
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: expressed_in
AKT1 Gene
gene · KG edge: expressed_in
ALDH1A3 — Aldehyde Dehydrogenase 1 Family Member A3
gene · KG edge: expressed_in

Knowledge Graph (12 edges)

CXCR4 activates SIRT1
NLRP3 regulates CXCR4
CXCR4 regulates STING
CXCL2 activates CXCR4
BMAL1 activates CXCR4
TAU regulates CXCR4
STING regulates CXCR4
TREM2 inhibits CXCR4
APOE inhibits CXCR4
TREM2 associated_with CXCR4

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