gene 2,018 words KG: CST3
Contents

CST3 Gene - Cystatin C

🧬 Gene Info
Gene SymbolCST3
Full NameCystatin C
Chromosome20p11.21
FunctionCysteine protease inhibition
Molecular Weight13 kDa
Amino Acids120 aa
UniProt IDP01034
NCBI Gene ID1471
Ensembl IDENSG00000141540
OMIM123400
GeneCardsCST3
Human Protein AtlasCST3
Associated DiseasesALS, Diabetes, Hypertension
InteractionsAmyloid, AMYLOID, CTSB, CTSD, CTSS, NPTX1
KG Connections46 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (4)

Complement C1q Mimetic Decoy Therapy
Score: 0.69
Complement C1QA Spatial Gradient in Cortical Layers
Score: 0.68
Complement C1q Subtype Switching
Score: 0.66
Complement-Mediated Synaptic Pruning Dysregulation
Score: 0.61

Related Analyses (5)

SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completed
4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived
Synaptic pruning by microglia in early AD
neurodegeneration · archived
Gene expression changes in aging mouse brain predicting neur
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (5)

s:** - Compare brain penetration in FcRn+/+ vs FcRn-/- mice
falsification · proposed · Score: 0.40
Proposed experiment from debate on Synaptic pruning by micro
falsification · proposed · Score: 0.40
Experiment: Autoimmune Hypothesis Testing in AD
clinical · proposed · Score: 0.40
Experimental: CAAR-T Cell Therapy for Autoantibody-Mediated
clinical · proposed · Score: 0.40
cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40

See Also (10)

Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: causes
APBB1
gene · KG edge: regulates
C1QA Gene
gene · KG edge: regulates
CLU — Clusterin (Apolipoprotein J)
gene · KG edge: regulates
CTSB Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

APP regulates CST3
CLU regulates CST3
CST3 regulates APBB1
CST3 regulates C1QA
CST3 activates CTSS
CST3 inhibits NPTX1
CST3 inhibits SERPINA3
CST3 inhibits NRXN2
CST3 inhibits VGF
CST3 activates CTSB

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