| Gene Symbol | CASP9 |
| Chromosome | 1p36.21 |
| Protein Type | Protease |
| Function | is a member of the cysteine-aspartic acid protease (caspase) family. |
| Amino Acids | 461 aa |
| Gene Type | Protein coding |
| Pathways | Akt, Nf-Κb, Pi3K, Toll-Like Receptor |
| UniProt ID | P55211 |
| Ensembl ID | ENSG00000132906 |
| GeneCards | CASP9 |
| Human Protein Atlas | CASP9 |
| Prodomain | N-terminal CARD (Caspase Recruitment Domain) for apoptosome interaction |
| Large Subunit (p35) | Contains the catalytic cysteine residue |
| Small Subunit (p12) | Completes the active site |
| Phosphorylation | Ser196 phosphorylation by Akt inhibits caspase-9 activity |
| Associated Diseases | neurodegeneration |
| Known Drugs/Compounds | Bpmc |
| Interactions | AKT, Anti-recoverin Antibodies, APOPTOSIS, ATM, EIF2A, GALT |
| KG Connections | 90 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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