| Gene Symbol | C1R |
| Full Name | Complement Component 1, R Subcomponent |
| Chromosome | 12p13.31 |
| Protein Type | Protease |
| Function | is a critical component of the innate immune system, providing defense against pathogens and contributing to tissue homeostasis. |
| Primary Expression | the brain, where they participate in synaptic remodeling, neuroinflammation, and neurodegenerative processes |
| Pathways | Complement |
| UniProt ID | P09871 |
| NCBI Gene ID | 715 |
| Ensembl ID | ENSG00000159403 |
| OMIM | 216950 |
| GeneCards | C1R |
| Human Protein Atlas | C1R |
| Zymogen state | Catalytic domain blocks active site |
| Activation cleavage | Generates active protease |
| Associated Diseases | Aging, Alzheimer, Senescence |
| Interactions | BIN1, C1S, CD47, CLN5, CR1, GENES |
| KG Connections | 92 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!