gene 540 words KG: FGFR2
Contents

FGFR2 — Fibroblast Growth Factor Receptor 2

🧬 Gene Info
Gene SymbolFGFR2
Full NameFibroblast Growth Factor Receptor 2
Chromosome10q26
FunctionFGFR2 encodes fibroblast growth factor receptor 2, a receptor tyrosine kinase that primarily binds FGF7 and FGF10 (ligands with high specificity for FGFR2IIIb isoform).
Primary Expressionneural progenitors, astrocytes, and some neurons
PathwaysApoptosis, Chemoresistance, Stem Cell
UniProt ID[P21802](https://www.uniprot.org/uniprot/P21802)
Ensembl IDENSG00000166468
OMIM176943
GeneCardsFGFR2
Human Protein AtlasFGFR2
Associated DiseasesCancer, Cardiac, Ischemia
InteractionsActin, App, ASTROCYTE, ASTROCYTES, AUTOPHAGY, B3GALT6
KG Connections146 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

TP53 regulates FGFR2
FGFR2 regulates GFRA1
IDH1 therapeutic_target FGFR2
BRAF therapeutic_target FGFR2
CD44 activates FGFR2
FGFR2 inhibits EGFR
BRAF biomarker_for FGFR2
NRG1 biomarker_for FGFR2
TP53 biomarker_for FGFR2
FGFR1 biomarker_for FGFR2

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