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cell 1,086 words KG: GABA
Contents

VTA GABAergic Neurons

🧫 Cell Type Info
Cell TypeGABA
Key PathwaysGABAergic Signaling
Associated DiseasesALS, Als, Alzheimer, Alzheimer'S Disease, Amyotrophic Lateral Sclerosis, Ataxia
Related GenesATG, GABARAP, HDAC3, LC3, MTOR, MTORC1
Linked Hypotheses246 hypotheses

No AI portrait yet

Knowledge Graph

Related Hypotheses (8)

APOE-Dependent Autophagy Restoration
Score: 0.85Circadian-Synchronized Proteostasis Enhancement
Score: 0.74The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction
Score: 0.65TFEB-PGC1α Mitochondrial-Lysosomal Decoupling
Score: 0.62Senescent Cell Mitochondrial DNA Release
Score: 0.74

Related Analyses (9)

Senolytic therapy for age-related neurodegeneration
neurodegeneration · archivedSelective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archivedBlood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archivedMitochondrial transfer between astrocytes and neurons
neurodegeneration · archivedCell type vulnerability in Alzheimer's Disease (SEA-AD data)
neurodegeneration · archived

Related Experiments (8)

Mechanism: Selective Vulnerability of Dopaminergic Neurons i
validation · proposed · Score: 0.40ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40Trehalose-induced lysosomal changes and TFEB activation
exploratory · proposed · Score: 0.90iPSC-NPC effects on astrocytes in vitro ICH model
exploratory · proposed · Score: 0.90Trehalose-induced lysosomal membrane permeabilization and TF
exploratory · proposed · Score: 0.90

Knowledge Graph (12 edges)

GABA associated_with MTOR
GABA associated_with TFEB
AKT associated_with GABA
BACE1 associated_with GABA
TAU associated_with GABA
GABA associated_with neuroinflammation
GABA associated_with serotonin
GABA associated_with GABAergic neurons
GABA interacts_with GABARAP
FLCN interacts_with GABA

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