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cell 780 words KG: GABA
Contents

Reticular Thalamic Nucleus GABAergic Neurons

🧫 Cell Type Info
Cell TypeGABA
Key PathwaysGABAergic Signaling
Associated DiseasesALS, Als, Alzheimer, Alzheimer'S Disease, Amyotrophic Lateral Sclerosis, Ataxia
Related GenesATG, GABA, GABARAP, HDAC3, LC3, MTOR
Linked Hypotheses331 hypotheses

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Knowledge Graph

Agent Input

Related Hypotheses (9)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.38APOE-Dependent Autophagy Restoration
Score: 0.88Circadian-Synchronized Proteostasis Enhancement
Score: 0.74The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction
Score: 0.65TFEB-PGC1α Mitochondrial-Lysosomal Decoupling
Score: 0.62Senescent Cell Mitochondrial DNA Release
Score: 0.74Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.73Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.65Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.53

Related Analyses (11)

RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archivedBlood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archivedSenolytic therapy for age-related neurodegeneration
neurodegeneration · archivedWhat are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completedSelective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived

Related Experiments (7)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40Trehalose-induced lysosomal changes and TFEB activation
exploratory · proposed · Score: 0.90Trehalose-induced lysosomal membrane permeabilization and TF
exploratory · proposed · Score: 0.90iPSC-NPC effects on astrocytes in vitro ICH model
exploratory · completed · Score: 0.90iPSC-NPC transplantation in ICH animal model
validation · proposed · Score: 0.85

Knowledge Graph (12 edges)

GABA associated_with MTOR
GABA associated_with TFEB
AKT associated_with GABA
BACE1 associated_with GABA
TAU associated_with GABA
GABA associated_with neuroinflammation
GABA associated_with serotonin
GABA associated_with GABAergic neurons
GABA interacts_with GABARAP
FLCN interacts_with GABA

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