protein 1,462 words KG: AKT1
Contents

AKT1 Protein (Protein Kinase B Alpha)

🔬 Protein Info
Gene SymbolAKT1
Protein TypeKinase
Functionis a serine/threonine protein kinase that serves as a central hub in the PI3K/AKT/mTOR signaling pathway, one of the most critical survival and growth signaling cascades in neurons.
Amino Acids480 aa
PathwaysAkt, Apoptosis, Autophagy, Immune Response, Mapk
Ensembl IDENSG00000142208
GeneCardsAKT1
Human Protein AtlasAKT1
Associated DiseasesAging, Als, Alzheimer, Alzheimer's disease
Known Drugs/CompoundsAndrographis paniculata, Atbc, berberine, Coumestrol, COUMESTROL, DEP
InteractionsACTB, Actin, AGING, AKT, ALZHEIMER, ALZHEIMER DISEASE
KG Connections1550 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

UniProtWikipedia

Related Hypotheses (1)

Brain Insulin Resistance with Glucose Transporter Dysfunctio
Score: 0.60

Related Analyses (1)

Metabolic reprogramming in neurodegenerative disease
neurodegeneration · completed

Knowledge Graph (12 edges)

COUMESTROL interacts_with AKT1
OPTN interacts_with AKT1
CASP3 regulates AKT1
AKT1 regulates CALCOCO2
AKT1 regulates CGAS
AKT1 regulates CFTR
AKT1 interacts_with SQSTM1
AKT1 interacts_with RPS6KB1
AKT1 interacts_with GRB2
AKT1 interacts_with RHEB

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